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Kriadex Clonazepam 2 mg 60 tabs

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Clonazepam for sleep

Clonazepam is a benzodiazepine class tranquilizer. The drug is taken to treat seizures and panic disorders. 

The drug has a sedative effect on the body but does not have a strong sleeping effect. This is caused by the effect of the active components on the nonspecific thalamic nuclei. Also, the active components act on the reticular formation of the brain stem. 

The hypnotic effect is manifested by a decrease in anxiety, fear, and other neurotic symptoms.

How long does Clonazepam stay in the system?

When Clonazepam (2mg) is used orally, the bioavailability is over 90%. In an adult, the drug stays in the body for 10-12 hours. In a child, the drug remains in the body for 6-8 hours.

Clonazepam half life

The half-life of the drug in the body varies between 18-20 hours. It’s excreted with the urine. 

Clonazepam: urine detection time

The drug stays in the urine for 18-20 hours. If the drug was taken to relieve symptoms of insomnia (e.g., in shallow, frequently interrupted sleep), a slight residual effect persists for the first half of the day.

Clonazepam vs. Lorazepam

Clonazepam belongs to the group of anticonvulsants. Lorazepam is an anti-anxiety drug (anxiolytic).

Unlike Clonazepam, which is only taken orally, Lorazepam is administered by vein. Sublingual and intramuscular administration of the drug is also allowed. 

Clonazepam is a long-acting benzodiazepine with a rapid onset (1-4 hours). Lorazepam is a short-acting benzodiazepine with a half-life of 15 hours.

Clonazepam and alcohol

Women are allowed to take the Clonazepam pill 24 hours before and 14 hours after taking alcoholic products. Men are allowed to take the drug 18 hours before the use of alcohol and 8 hours after the use of alcoholic beverages.

The simultaneous use of alcohol-containing products and Clonazepam is prohibited, otherwise the blood pressure decreases and the heart rate increases. In the most severe cases, epileptic seizures develop.

Clonazepam vs. Xanax

Clonazepam is an intermediate-acting medication. Xanax refers to short-acting drugs. In general, the half-life of this medication ranges from 6 to 12 hours.

The greatest efficacy of Clonazepam is observed within 4 hours. The greatest efficacy of Xanax is present for 60-120 minutes.

The shorter half-life of Xanax is due to the rapid development of drug tolerance. When using this medication for very long periods of time, a constant increase in the dose is necessary to achieve the desired effect.

Clonazepam is taken as part of therapy for quite a long time, while Xanax is prescribed for a short period of time. 

Against the background of the rapid elimination of Xanax from the body, negative reactions are present for 2-4 hours. After using Clonazepam, side effects are present for 2-3 days. 

How to not be tired on Clonazepam?

Against the background of sudden discontinuation of 2 mg Clonazepam or if the dosage is reduced, withdrawal syndrome occurs. This is quite a dangerous condition. Serious risks occur both when the recommended dosage is increased and when the medication is taken for a long period of time.

Before you stop taking the medication or reduce the dosage, you should get a consultation from your doctor and try to adhere to his recommendations.

Clonazepam overdose

The intensity of symptoms of overdose and intoxication depends on the age characteristics of the body, weight, individual reaction to the components that are in the composition of the drug.

Some patients experience nystagmus (uncontrolled rhythmic movements of the eyeballs), ataxia (a condition characterized by motor disorder. There is a lack of coordination of muscle movements), as well as dysarthria (speech is disturbed, vocal cords do not function properly, there is a disorder of the functioning of the respiratory and facial muscles). 

In some cases, Clonazepam potentiates the effects of other drugs that have a depressing effect on the central nervous system. 

Some elderly people fall into a coma while taking the drug, the duration of which (depending on the severity of the condition) varies from 6 hours to several days. Individuals with severe chronic obstructive airway disease complain of symptoms of respiratory depression. 

If a person has taken the Clonazepam pill as monotherapy, an overdose causes serious harm to his or her health. Hypotension (a severe drop in BP accompanied by weakness, dizziness, palpitations, shortness of breath, and loss of consciousness) occurs. Some patients complain of symptoms of aphlexia (choking).

To help the person, gastric lavage is performed. To stabilize the condition, medications are prescribed to regulate the cardiac, vascular, and central nervous system.

Does Clonazepam cause weight gain?

When taking this drug, there is a slight possibility of weight gain. But more often the opposite effect is observed: the person taking this drug loses weight.

According to clinical studies, less than 1% of people gain weight while taking Clonazepam. According to doctors, weight gain is a side effect of the drug.

Does Clonazepam lower blood pressure?

A decrease in blood pressure is an adverse reaction of taking this drug. This condition is often combined with tachycardia. These symptoms are especially common in older people.

Clonazepam and pregnancy

Taking Clonazepam pill when carrying a fetus is not recommended: the active ingredients of the drug penetrate the placental barrier. It is also forbidden to take this drug while breastfeeding: it is excreted with breast milk.

The drug is prescribed to a woman only if the therapeutic benefits far exceed the probable risks to the fetus. If the expectant mother complains of severe seizures, the use of the drug is carried out under strict medical supervision. 

It is categorically forbidden to take Clonazepam in late pregnancy. Otherwise, there is a serious risk of withdrawal effects in the child. These signs are present for several months.

Clonazepam for seizures

By enhancing presynaptic inhibition, the anticonvulsant effect is realized. Epileptogenic activity is suppressed. Excitation of the epileptogenic focus is not relieved.

Against the background of taking Clonazepam pill, the paroxysmal activity of different types is quickly suppressed. This applies to "spike waves" and "spikes". The beneficial effect of the drug on the body in the development of a generalized (focal) form of epilepsy has been proven.

Clonazepam for insomnia

The drug has an effect on sleep: after using Clonazepam, the person falls asleep faster. The quality of sleep improves noticeably, nightly awakenings stop. The duration of sleep does not change, but the person sleeps better against the background of deep sleep.

Ativan and Clonazepam

Ativan is an anxiolytic. Ways to use the drug: intravenous, sublingual, intramuscular. The drug belongs to the short-acting benzodiazepines. The half-life of the drug is 15 hours.

Clonazepam and Alprazolam

The use of Clonazepam is recommended in the therapy of akinetic seizures and myoclonus. The use of Alprazolam is recommended when it is necessary to eliminate acute panic attacks and anxiety disorders. The drugs have different effects: this is due both to their composition and to differences in their chemical structure.

The initial dosage of Clonazepam is 0.25 mg. It is recommended that the drug be taken not more than 2 times/24 hours. 

For panic attacks, Alprazolam is prescribed in a dosage of 0.5 mg. The drug should be taken more intensively - 3 times/24 h. 

Clonazepam and Valium

Valium (Diazepam), like Clonazepam, is prescribed for the treatment of anxiety disorders. For severe seizures, trembling hands and feet, delirium, and other similar signs, Valium is allowed as part of the therapy of some neurological diseases. It is permitted to take this drug when hallucinations associated with alcohol withdrawal syndrome occur.

The use of Clonazepam is recommended for akinetic and other similar seizures. It is permitted to take this medication when symptoms of Lennox-Gasto syndrome appear.

Valium is available in tablets, as well as in the form of a solution for injection into a vein/muscle, injections, and a rectal gel.

Clonazepam and Melatonin

The drug Melatonin is a synthetic analog of the epiphysis hormone melatonin. Its main purpose is to normalize circadian rhythms. The remedy has adaptogenic, sedative, and hypnotic effects. 

When using this drug, the concentration of GABA increases in the midbrain and hypothalamus and there is a change in the activity of pyridoxal kinase, which takes part in the synthesis of dopamine and serotonin.

Clonazepam. Addiction

The development of Clonazepam pill dependence occurs when this medication is used for too long. When a person suddenly stops drinking the drug, a "withdrawal syndrome" develops. The person may complain of intense headaches that occur spontaneously. Some patients notice the occurrence of muscle pains of different localization and character (myalgia).

The person becomes more anxious and tense. This condition is often accompanied by panic attacks. Some people experience sudden memory lapses. Irritability and irascibility may occur.

There is also the possibility of developing hyperacusis (a hearing disorder characterized by hypersensitivity with respect to certain frequencies and ranges of sound volume). Hypersensitivity (light, tactile) can be accompanied by paresthesias. 

In the most severe cases, development of derealization is observed (in this case, perception of the world around is impaired. It seems to the person that everything that occurs around him is unreal) and depersonalization in which the self-perception of the personality is disturbed.

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